Solute Diffusion via CT
CT-Based Diffusion in Cartilage
We investigated how imaging parameters and solution properties affect measurements of CT contrast diffusion within cartilage. The analysis showed that both acquisition settings and solute composition strongly influence apparent diffusivity. These findings underscore the importance of experimental control in quantitative CT studies of cartilage transport.
Segmenting Cartilage in CT Arthrography
We developed and validated a watershed-based approach for delineating cartilage surfaces from time-series CT arthrograms. The method addresses boundary blurring caused by contrast diffusion and enables accurate morphological tracking over sequential scans. These results improve surface reconstruction essential for dynamic cartilage imaging and disease progression studies.
Diffusion Mapping in Meniscus by CT
We applied dynamic contrast-enhanced CT to quantify solute diffusion through the knee meniscus. Time-resolved imaging revealed spatial variation in transport consistent with structural anisotropy. This approach links tissue architecture with transport properties in both healthy and diseased states.