Soft Tissue Biomechanics and Validation
Validating MRI Stiffness in Heart Models
Using synthetic heart phantoms, we validated MRI-derived estimates of myocardial stiffness. Comparison with mechanical reference testing showed strong agreement between imaging and experimental measurements. This validation supports the use of MRI for noninvasive stiffness mapping in cardiac biomechanics research.
Arterial Wall Stiffness and Flow
We analyzed how vessel wall stiffness alters local hemodynamics in a synthetic aortic model. High-resolution flow measurements revealed nonlinear changes in velocity fields and pressure gradients with increasing stiffness. These findings provide insight into vascular remodeling and inform predictive models of cardiovascular disease progression.
Mechanical Behavior of Airway Tissue
We characterized heterogeneous and anisotropic mechanical responses of airway tissue using combined elastic and viscoelastic modeling. The results revealed strong directional dependence and nonlinearity under physiological strain. These insights improve understanding of airway wall mechanics and support computational respiratory simulations.