Soft Tissue Biomechanics Laboratory
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Welcome

The research activities of the Soft Tissue Biomechanics Laboratory focus on the function, degeneration and regeneration of articular cartilage and fibrocartilage, with an emphasis on understanding the complex interactions between biophysical and biochemical cues in controlling cell behavior. Our approach combines contemporary approaches from a variety of disciplines including experimental and theoretical mechanics, cell and tissue culture, imaging, biochemistry and molecular biology.

Welcome to our website!

Lab meetings for Autumn 2009: Mondays, 12:00pm, Durand 247 (first meeting Monday, October 5)

Reconstructed EPIC-µCT images isolating the articular cartilage layer from a rabbit distal femur.  AWP Comparison of the extracellular matrix produced by bone marrow stromal cells and articular chondrocytes in 3D engineered constructs.  JTC
Immunofluorescence staining showing colocalization of collagen I and collagen VI in saggital cross-sections of the bovine meniscus.  EJV Custom designed apparatus for applying cyclic tension to engineered tissue constructs in tissue culture.  JTC/EJV

History

The Soft Tissue Biomechanics Laboratory was established in 1998 at the Georgia Institute of Technology within the George W. Woodruff School of Mechanical Engineering. The lab was affiliated with the Parker H. Petit Institute for Bioengineering and Bioscience and the Georgia Tech/Emory Center for the Engineering of Living Tissues.

In 2007, the Soft Tissue Biomechanics Laboratory moved from Georgia Tech to the Department of Mechanical Engineering at Stanford University.

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